By Peter Braude, Alison Taylor
Written via a staff of infertility specialists, this consultant addresses the complicated topic of subfertility. It starts off with prognosis within the female and male ahead of offering suggestion on all types of assisted perception in addition to counselling support with remedy judgements.
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Additional info for Alison Taylor, ABC of Subfertility
ICSI is a highly specialised variant of IVF treatment, in which fertilisation is achieved by the injection of a single sperm directly into the cytoplasm of the egg. Only mature eggs (those that have extruded the first polar body and hence are at the second metaphase of meiosis) are suitable for injection with prepared sperm. As ICSI is usually used when sperm quality is extremely poor, each sperm can be examined and selected for normality of its morphology before being picked up individually with a fine glass needle and inserted directly into the cytoplasm of the egg.
Management of infertility for the MRCOG and beyond. London: RCOG Press, 2000 x Winston R, Hardy K. Are we ignoring potential dangers of in vitro fertilization and related treatments? Nat Cell Biol 2002:4;14-8 x Ombelet W, Menkveld R, Kruger TF, Steeno O. Sperm morphology assessment: historical review in relation to fertility. Hum Reprod Update 1995;1:543-57 x Rowe PJ, Comhaire FH, Hargreave TB, Mellows HJ. WHO manual for the standardised investigation and diagnosis of the infertile couple. Cambridge: Cambridge University Press, 1999 Paula Rowell is senior embryologist at the Guy’s and St Thomas’s assisted conception unit, London The ABC of subfertility is edited by Peter Braude, professor and head of department of women’s health, Guy’s, King’s, and St Thomas’s School of Medicine, London, and Alison Taylor, consultant in reproductive medicine and director of the Guy’s and St Thomas’s assisted conception unit.
The success of the freeze-thaw process and subsequent transfer can depend on the clinic where it is done. uk/ForPatients). Straw containing frozen embryos being removed from liquid nitrogen storage dewar for thawing before embryo transfer Sperm cryopreservation Although cryopreservation of semen from animals and humans has been done for many years, and refinements of the technology have allowed increases in the yield of motile sperm surviving, fresh samples are still about 30% better in quality than frozen samples.